Help needed.

Help needed.
is there any pro can solve the problem?

'make sure the disk is not full or write-protected and the file is not currently in use' ----that is the message i got when i try to delete a file which located in program file.

highly appreciated

文件正在使用中。
比如：某個影音播放軟體正打開你要刪除的文件。
解決：用影音播放軟體打開另一個文件，然後刪除你要刪除的文件。
以此類推。

thank your very much for your advice, pro. in my opinion, this might be a shared soft ware(seekmo) and someone may be using somewhere in the world. i think what i need to do is to delete it from the safe mode, however it is beyond my understanding on how to process from safe mode. once again thank you for you suggestion and i am really appreciated.