看出問題來沒?器官重量、直徑、肌苷清除率、鹼性磷酸酶等指標都是計量資料。理所應當選用t檢驗和方差分析進行統計學分析。但是,作者只接受「有差異」的統計結果。如果統計結果顯示「無差異」,他們就認定這種統計方法「is insufficient in these studies」。為了千方百計找出「差異」來,作者寧可捨棄了經典的,統計效力高的檢驗方法,改用人為因素很大,統計效力低的非參檢驗。可以看出,作者是先下結論,后做研究。
這個研究水平不高,問題不小
這個包括諾貝爾科學獎獲得者、分子遺傳學轉家馬里奧·卡佩奇(Mario R. Capecchi)等三位美國國家科學院院士的編委會審稿水平也太差了.
Mario Renato Capecchi (born 6 October 1937) is an Italian-born American molecular geneticist and a co-winner of the 2007 Nobel Prize in Physiology or Medicine for discovering a method for introducing homologous recombination in mice employing embryonic stem cells, with Martin Evans and Oliver Smithies.[1] He is currently Distinguished Professor of Human Genetics and Biology at the University of Utah School of Medicine, which he joined in 1973.
在Journal of Animal and Feed Sciences, 2010年 19卷, 163頁明確指出,De Vendomois et al., 2009的研究存在「Weaknesses in the statistical methods used for reanalysis」的缺陷。
Flachowsky, G., Wenk, C. The role of animal feeding trials for the nutritional and safety assessment of feeds from genetically modified plants. Journal of Animal and Feed Sciences, 19, 2010, 149–170
You don't seem to understand the journal reviewing process very well. Usually an Associated Editor gets the manuscript and the letter from the authors who recommends a list of potential reviewers who are qualified to review their work. Most time, although it is not always, two or three or more reviewers are contacted for their willingness to review the submitted work. Is the editors call if any one of the listed candidates get this invitation. It is these invited reviewers who make most of decisions if this work need to make change or not, if changes are made, are these good enough or not. The journal editorial board most time goes along with the comments made by the majority of the reviewers. Only when the reviewers send in split opinions, the editor will have his/her input. A relatively poor journal like this, I would guess 2 reviewers at the most will be invited. If these two reviewers are in friend with the author, they could get an easy ride.