(1)肝功能損傷:一些皮膚病(主要是濕疹或牛皮癬)患者在服用中草藥后,出現了肝功能異常。據 <<lancel>>和<<British jounal of medicine>>等權威醫學雜誌報導(3-7),有六例均為服用中草藥后出現肝功能異常(其毒性成分曾被懷疑是白蘚皮)。多為個案報導。多數病人有噁心,疲勞,黃疸等癥狀,血檢提示其肝功能異常一多由biliruhin,AIK,AST,ALT及B一超,活檢等指標異常所證實。其中二例因肝功能異常行肝移植手術未獲成功而死亡。其餘患者均在停服中藥后肝功能恢復正常。其中一例在肝功能恢復正常後繼續服用中藥,肝功能又不正常;再次停用中藥,肝功能又恢復正常。無一例形成慢性持續性肝病的報導。
(3)充血性心力衰竭:1997年<<British.journal of Dermatology>>報導(11)在曼徹斯特一婦女服用中藥治療濕疹;二周后出現充血性心力衰竭,被診斷為中毒性心肌病。儘管此患者有甲狀腺中毒症與陣發性心動過速的既往史,但諸症在近2-3年一直控制良好並無發作。其所服毒性成分被懷疑是甘草。大劑量甘草被認為促進鈉的貯留和鉀的流失,從而導致水與電介質的紊亂。對此類易感患者,水液貯留於心肌引起心肌病與心衰發生。該患者經過強心,利尿等西醫常規治療,三周盾病變完全控制。
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