方舟子遇襲案開庭 方舟子的人氣為何急轉直下

2010/10/10  消息來源：華龍網  


　　
　　肖傳國今日受審 方舟子、方玄昌不會親自到庭索賠


　　近日從網上傳來消息，涉嫌毆打著名打假英雄的外科醫生肖傳國等一干人犯已經由北京市公安局移送到了檢察機關，對肖傳國等一干涉嫌案犯的處理，想必就快有結果了吧？糾纏了百姓們數月的沸沸揚揚的方舟子挨打案看來真的會塵埃落定了。

　　遙想「方案」初發之時，方舟子先生一夜間紅遍了大江南北，網路及各種媒體幾乎以一邊倒的壓倒優勢聲援並支持著方舟子先生，不少人將方舟子先生當成了社會的良知，真理的化生，新時代中國新文化運動的代表人物之一，某網站公布了一個所謂的「網路調查」，更宣布出了一個誇張的數據，說是有96.5%的網民都是支持方先生的。而隨著方舟子案的告破，以及案犯肖傳國等人的即將定刑，人們卻意外地發現目前支持方舟子先生的人反倒越來越少了，網路間，質疑和否定方舟子的文章鋪天蓋地，而一些主流媒體在發布挺方雄文的時候也往往顯得遮遮掩掩，羞羞答答，欲言又止，越來越沒那麼自信，絲毫沒有先前的氣壯山河，橫掃千軍如卷席那樣的氣勢了。

　　究竟是什麼原因造成了方先生人氣的急轉直下，在支持方先生的態度上發生了大逆轉？我估計主要是因為「方案」初發之時，網民或許對方先生其人其實並不是十分了解，而當時的主流媒體又幾乎以一邊倒的態勢早就將方先生樹立成了我們的民族英雄，打假勇士，網民們懵懵懂懂，人云亦云，眼見著自己的英雄挨打，豈能不義憤填膺，豈能不「應者營集」? 而隨著人們對方舟子其人其事的深入了解，人們越來越明白的事情的真相，越來越看清了方舟子的為人，故縱然擊傷方舟子的案犯果如方舟子先前所預料的那樣是肖傳國，縱然方舟子先生並沒有像人們當初所懷疑的那樣是在報假案，但料想中的「挺方」熱潮還是沒有像先前預計那樣滾滾而至，相反人們卻越來越懷疑起這位傳說中的打假英雄，對他的做法與為人越來越反感，對他的所謂的「打假」越來越質疑，更有甚者還力挺起肖傳國來了（這當然是不應該的，個人以為）。

　　方舟子先生的打假儘管名氣很大，他的英雄事迹傳遍了大江南北，幾乎家喻戶曉，然則冷靜分析起來，其實他的十年打假並沒有取得什麼實質性的重大的成果，固然，方先生的打假，瞄準的都是些名人要人或紅人，但客觀而論，但這些人其實都均非罪大惡極，十惡不赦，均不是貪官污吏及禍國殃民之輩，比方像方舟子近期打擊的錢學森，錢偉長，唐駿，肖傳國，孫見坤，李一等，而真正危害百姓，傷害國家，真正禍國殃民，罪大惡極，十惡不赦貪官污吏之輩，方舟子先生至今尚未打擊過，當然也沒有揪出過，一可能是他老人家尚未遇到此類壞人，二可能是黃河已清，咱中國已經將這些壞人清理乾淨，無須勞煩舟子動手（以上兩條都不能怪方先生），第三，也有可能是他老先生的打假根本就是假打，不敢打真正的大假，故民間有雲，「舟子打假，只打蒼蠅，不打老虎；只打學者，不打貪官」，所以其打假的效果並不不彰，對社會的益處並不大，老百姓們明白了這個道理之後當然也就並不擁戴他了。

　　儘管方舟子先生打擊的對象如像錢學森，錢偉長，以及他引以為傲的唐駿，肖傳國，孫見坤，李一（我對這個人不太了解，暫且不論）等，也許都有這樣那樣的問題，然而這些問題，或許都是些枝節問題，或許並不是太危害社會，危害百姓的利益，比方唐駿，（此乃方舟子最為自豪的功績之一），由方舟子揭露出來的假博士一說，或許方說的事實，但是，唐駿是不是博士其實並不重要，考唐駿之進入微軟而一舉成名，其實並非他靠了假博士的文憑而混入微軟，實靠著人家的銷售業績，管理本事而榮膺了打工皇帝，這都是有案可稽的。唐之文憑造假，只是他的個人虛榮，但他並沒有靠這張假文憑騙吃，騙喝，騙財，騙色，並沒有帶來重大的社會危害，亦沒有妨礙他人，老方成功地揭露出了唐駿，只能說明老方善於發現別人的瑕疵，善於發現別人的缺陷與創傷，算不上什麼有益於社會，因為即使再揪十個唐駿，也與老百姓關係不大，而照樣有很多人還是愛虛榮，還是愛擺顯，還是要去買野雞大學的文憑。方舟子如果真要打擊假文憑，實應該打擊造假的源頭，取締像美國太平洋大學那樣的野雞大學。

　　又比方方舟子打肖傳國，先不說他之打肖是出於十年來的個人恩怨，冤冤相報，就是在學術方面，目前也尚無定論，不能說老方就一定正確，亦不能說老肖的「反射弧理論」就是一定偽科學，而老方的所謂的「打假」，其實也算不上是一種真正的打假，只能說是一種質疑，一種提醒，一種商榷，一種爭論，在客觀的鑒定沒有出來之前，尚不能認為方舟子就是在「打假」，從而上升到打假層面予以方舟子表彰，予以吹捧和神話，當然也就算不上方舟子打假的「豐功偉績」了。

　　再比如錢學森與錢偉長，此二人固然非神人與完人，難免會有這樣那樣的缺點，但方先生對二錢的所謂的打假，卻實在讓人覺得很古怪，也難以接受。二錢活著的時候，方舟子對他們連半個字都不加置評，二錢剛去世，屍骨尚未寒，他就立馬跳將出來進行他那所謂的義正詞嚴的「打假」，反正死無對證，千秋功罪任由他方舟子評說，故方舟子的打假當然會令老百姓感到不滿。而且方先生對二錢的打擊，表面上雖在揭發他們身上的一兩個造假事件，其實很明顯是企圖將這二人徹底推翻，看他那架勢，簡直非要把二錢打成「偽科學家」不可！魯迅先生告誡中國的批評家道：「你在指出別人的缺點和別人的錯誤的同時，亦要同時指出這個人的哪些思想和行為對社會還有有益之處，愛人身上長了幾個瘡，總不至於就請律師來離婚吧？正如一個有爛疤的蘋果，批評家在指出這個爛疤的同時，還應當指出這蘋果的那些地方還沒有爛，還可以吃得，否則你就是一個不合格的批評家或者偽批評家。」方舟子先生的打假在揭露了別人某些造假之後，總是恨不得把人一杆子打死，從來沒有指出過斯人還有什麼地方值得肯定的地方，這不能說這是方舟子式的打假的一個重大缺陷，或許方舟子先生並不是一個真正的打假者，而正是魯迅先生所謂的那種不合格的批評家或偽批評家吧。

　　金無足赤，人無完人，魯迅先生道：「即便是戰士，他的身上也還是有缺陷，也還是有疤痕，而蒼蠅是最善於發見別人的疤痕和缺陷的角色，一旦發現了別人的缺點，就會啜著，營營的叫著，一面拚命地吮吸，一面拉出許多蠅屎來，在人家的皮膚上，給人以證明他是個怎樣不幹凈的東西。」

　　生著翅子的並不一定都是天使，也有可能是鳥人；最善於發現別人缺點的人，並不一定都是鬥士，說不定其實只是一隻蒼蠅！但即便蒼蠅發現了戰士的缺點，戰士依然是戰士，再完美的蒼蠅終竟不過是蒼蠅，而永遠也不可能成為戰士，方舟子先生和錢學森錢偉長這二位為中國人民做出過重大貢獻的科學家比起來，究竟誰是蒼蠅，誰是戰士？老百姓心中其實是有桿秤的，哪怕方舟子們把口號喊得震天價響，把「科學」的大旗舉得再高，其實也是改變不了這個事實的。

　　方舟子先生人氣的急轉直下，令人唏噓，讓人惋惜，但他的沒落，或許正與他的這種有缺陷的打假方式有關，勢所必至，理有固然，但願我們的打假英雄能夠與時俱進，改變其打假方式，不要因沒落而墮落，則中國幸甚，百姓幸甚！

不管怎樣, 能打假就行. 總得有人打假.
很多人支持肖傳國, 難道肖傳國造假對?
難道肖傳國打人對?

因為五毛黨力量太大了唄

不管怎樣, 能打假就行. 總得有人打假.
很多人支持肖傳國, 難道肖傳國造假對?
難道肖傳國打人對?
fantasyfun 發表於 2010-10-10 23:39

椰子代表感恩的心  2007年05月23日08:28 大河網-大河報
　　



豫瓊媒體聯手尋醫，鄭大教授治好了海南小善善的怪病，小善善的父親昨天帶著親手從海南砍下的1000個椰子前來感謝河南恩人

　　核心提示

　　282天中，4名鄭州大學的教授徹底改變了一個小男孩的命運。

　　這個可愛又可憐的孩子是海南人，名叫善善。他從小就沒有小便和大便的感覺，每次大便總是靠媽媽用手指摳出，小便只能一滴一滴往外憋。

　　去年，為了救助善善垂危的生命，本報與海南《南國都市報》聯合掀起一股救助善善的熱潮（詳見去年7月22日、8月12日、8月14日報道）。去年8月13日，小善善被接到鄭州大學神經泌尿外科研究中心免費手術，以後的日子裡，善善在眾多河南、海南人的關注中逐漸康復……

　　昨天下午，小善善的爸爸歷時4天、行程數千公里，把親手砍下的1000個椰子送到了鄭州大學，「感謝教授、感謝河南恩人！」善善爸爸流著淚說。

　　□記者黃普磊首席記者路紅文首席記者張鴻飛圖

　　豫瓊媒體聯手救助小可憐

　　現在已經5歲的小善善一出生，尾椎處便有一個疙瘩，用手去摸，裡面有個小洞。善善的肚子常被尿憋得鼓鼓的，疼得他一邊用手猛抓「小雞雞」，一邊哭喊：「媽媽，我的『小雞雞』很疼！」醫生告訴善善的爸爸和媽媽，這種病的名字叫先天性脊椎裂，先天性脊椎裂是個世界性的醫學難題，幾年後孩子將會癱瘓，得上這種病的孩子一般都難以活到成人。

　　小善善的父母王亞伍夫婦一度想放棄，聰明的善善似乎感覺到了什麼，他不止一次地對爸爸媽媽說：「你們不要丟掉我！」無奈之下，王亞伍夫婦找到了海南的《南國都市報》。《南國都市報》的報道迅速在海南掀起了一股救助善善的熱潮，幾天內，海南人為善善捐款數萬元。

　　聽說鄭州有家醫院能治此病，《南國都市報》向本報發出求助，2006年7月本報刊發報道，替小善善尋找醫生。

　　2006年8月13日，在河南、海南眾多媒體的共同關注下，鄭州大學神經泌尿外科研究中心為善善免費進行手術，研究中心主任、國家973項目首席科學家、博士生導師肖傳國教授和博士生導師高曉群、杜茂信、何朝宏教授聯手為其進行了「肖氏反射弧」手術。

　　海南小善善的怪病治好了

　　昨天上午9時，記者來到鄭州大學神經泌尿外科研究中心二樓病房。「善善，想不想撒尿呀？」記者問道。「不尿，爸爸說要來，我要等著爸爸來才尿。」小善善仰起臉對記者說。「他昨天晚上知道他爸爸要來，高興得一直問爸爸什麼時候到呢！一直喝水憋尿呢！」媽媽陳冠香摸著兒子的頭說。

　　提起善善以前的病情，陳冠香眼圈有些發紅，「那些日子對我們全家來說都是噩夢，每天我都要用手給他摳大便，他尿不出來，每天都是那樣滴，四歲了天天都要帶尿不濕，別人家的孩子都上幼兒園，他卻不能上，正常的家庭永遠都無法理解我們這種患病孩子給全家帶來的痛苦。」

　　「我現在想尿尿，我忍不住了！」突然，善善對著媽媽喊道，說話間一股尿就從善善的小雞雞里流了出來，「用力，用力！」善善媽媽鼓勵說，「咦——」善善叫著用力，又一股尿流了出來。

　　「手術6個月後，善善就會自己大便了，前一段時間他尿尿還需要電流刺激，現在根本就不用了，尿不濕基本上也不用了！」善善媽媽說。「媽媽，我尿完了，快給我喝水，爸爸快來了！」小善善又喊道。

　　1000個椰子感謝河南恩人

　　昨天上午10時15分，一輛廂式貨車駛進鄭州大學神經泌尿外科研究中心，車廂兩側掛著大紅的條幅：感謝河南專家感謝河南教授。

　　車一停，王亞伍就迫不及待跳了下來，緊緊握住了高曉群教授的手。顧不上寒暄，王亞伍就忙著打開貨車後門，「高教授呀，這是我從老家專門給你們送來的椰子！我們全家感謝你們呀！」

　　車廂內，青青的椰子堆成了山。「這椰子一部分是我家自己樹上的，一部分是親戚樹上的，都是我們親手砍的，椰子是我們海南的特產，我就想到送些椰子給河南的恩人。」王亞伍說，椰子4天前就裝車了，他跟隨著物流公司的貨車，在路上走了4天。

　　就在兩個月前，小善善跟著媽媽再次到鄭州進行康復訓練，而爸爸王亞伍則留在海南家中。半個月前，高曉群教授把善善撒尿的錄像寄給了王亞伍，「我們農場的很多人都看了錄像，都好高興。」王亞伍說，幾天來，他都在考慮怎麼表達謝意，聯想到醫生們曾經好奇地問他椰子的情況，他就決定拉來一車椰子。

　　「椰子整整1000個，表達我們對河南人的幫助千恩萬謝！」王亞伍說很多老鄉、親戚聽說他要來河南謝恩，都讓他去砍他們家的椰子。

　　兒子一泡尿父親淚長流

　　「爸爸！」剛剛做完Ｂ超檢查的小善善被媽媽抱出來了，小傢伙還光著小屁股，看見爸爸他興奮地伸出了雙手，撲進了爸爸的懷裡。

　　還沒和爸爸親熱兩分鐘，小善善突然喊道：「我要尿尿。」轉眼間，眾目睽睽之下，被爸爸抱在懷中的小善善射出一道「水柱」。第一次看到兒子撒尿，王亞伍嘴唇顫抖著一聲沒吭。可能是剛剛做Ｂ超前喝了不少水，小善善足足尿了五六次，才宣布：「尿完了！」

　　「看到兒子撒尿，你高興不高興，怎麼不見你的笑容呢？」有記者問王亞伍，突然之間，王亞伍的淚水流了下來，「我太高興了，所以就想哭，我們一家人盼兒子撒尿盼了整整5年了呀！」王亞伍把臉貼在兒子的臉上，任淚水從臉上滑落。

　　為什麼反射弧建立了善善撒尿還要用力才能尿出？高曉群教授告訴記者，撒尿的行為是神經支配尿道括約肌收縮的結果，善善的神經雖然恢復了正常，但由於善善的括約肌從出生以來都沒有使用過，所以已經出現了退化，必須經過康復訓練才能逐漸恢復，數月之後，小善善將完全恢復正常。「可以確定，我們為小善善建立的人工反射弧已經百分之百成功了！」高曉群肯定地說。

　　百名貧困患者救助計劃啟動

　　「善善爸爸送來的椰子是我收到的最寶貴的禮物，我將永遠珍藏在我的記憶中，時時刻刻告訴我為老百姓做事有多自豪！」外出進行學術交流的肖傳國教授在接受記者電話採訪時激動地說。他再三委託記者向小善善全家表示感謝。

　　「醫療技術固然重要，醫者的人品更重要，讓我們在退休之前，盡量多幫助一些這樣無助的病人吧。」肖傳國在給高曉群的簡訊中寫道。

　　2006年鄭州市紅十字會已經和該研究中心聯合設立了該疾病的救助基金，專項救助全國貧困地區的先天性脊椎裂患者，一年來共有30多名患病兒童得到了該基金的救助。

　　「我們長期接觸這樣的患病孩子，深切體會到他們承受的痛苦已經達到人類難以承受的極限，作為研究這種疾病的教授，我們深深感到責任重大。」高曉群教授說。

　　「兩天前，我們得知善善爸爸要送椰子的消息后非常感動，中心領導和鄭州市紅十字會商量后決定從今年六一到2008年六一一年中再救助100名貧困患者，救助基金將根據患者實際情況實行救助。」高曉群教授說，「我們的計劃是不讓貧困阻礙孩子的生命！」

　　相關鏈接

　　善善所患疾病在學術上叫「神經源性膀胱」，是一種出生缺陷疾病，每1000名新生兒中即有1例，主要是其腦部發出的排尿信號無法傳給膀胱，造成大小便失控和不同程度的下肢功能障礙。

　　從上世紀80年代末開始，經過15年的潛心研究，肖傳國教授提出了國際公認的「肖氏反射弧」原理，這是外科領域裡僅有的幾項以中國人姓氏命名的手術原理。這一醫學新概念認為，利用截癱后廢用的體神經，通過手術將其與支配膀胱的內臟自主神經吻合雜交，形成人工的「皮膚－脊髓中樞－膀胱」排尿反射弧，學術界稱之為「肖氏反射弧」。

　　由於在理論和臨床實踐上的突出成就，肖傳國教授的研究成果獲得國家科技進步二等獎、中國高校自然科學一等獎，獲得吳階平醫學獎、何梁何利科學與技術進步獎，並兩次獲得國際神經泌尿外科界最高獎。

　　善善的爸爸第一次看到兒子小便得如此暢快

不管怎樣, 能打假就行. 總得有人打假.
很多人支持肖傳國, 難道肖傳國造假對?
難道肖傳國打人對?
fantasyfun 發表於 2010-10-10 23:39

美國患者經肖式手術治療后發的Email反饋
學者吳寶俊 發表於2010-10-10 0:53:50    科學網

下面這個帖子是肖傳國在2009年9月27日提供的美國患者經過肖式手術治療后給出的email反饋。
原帖地址是：http://www.starlakeporch.net/bbs/read.php?1,53703,53703#msg-53703
支撐疲憊之軀的甘泉 (2180 bytes)
Posted by: CG
Date: September 27, 2009 06:31AM


【最近的會上，在美國做的9個病人9個大便正常，9個能自己拉尿。下面是能找到的倆個病人EMAIL。還有許多難病解決后也很快樂】

Dr. Xiao,
Natasha was in today, if you recall she was the one on crutches with a nerve graft done Left L2 to S2
Baseline she was severely incontinent of urine between caths, severe constipation and incontinent of stool
She is now totally continent of stool and urine, senses her bladder full, senses her catheter going in and beginning to void on own
Urodynamics today demonstrated a stable bladder, normal sensation and an excellent reflex with stimulating the L4 Dermatome Bilaterally!! She voided to completion and we have great video of her bladder neck opening and the bladder emptying.
She is the second patient to have Bilateral reflex and both were high anastamoses (L2). Must be where the nerves cross.
I would consider Natasha a home run which is shocking! Thought I would let you know.
Kenneth M. Peters, M.D.
Chairman, Department of Urology


SCI, Gunshot 6 years. No control of bladder and bowel, Operated on Oct 8, 2008

****************************************************************************

Feb, 17, 2009
Okay everyone….Kelly asked me today to buy her some panties so she could
wear them at home. We went to the store and she picked them out. She
has had the same pair on for 2 hours now and they are not wet. She has
been to bathroom to void 4 times so far. She says that it feels like a
tickle in her tummy. I am crying and so thankful once again to God and
for both of you! She is so proud of herself. I just had to share this
with both of you.

March 1, 2009：
Kelly is now beginning to have some very consistent success. She has been wearing panties all week. Everywhere we go to school, play practice, etc... and she has not had an accident. Also it seems her ability to "hold it" is improving, so if a bathroom is not close by she can wait a tiny bit until we find one. I asked her what she thought the difference is and she said that she is feeling it more. She also looked at me with those blue eyes and that freckled face and said "Mom, wishes really do come true!" Once again, I cried.

回復 2# fantasyfun


    肖傳國雖打人犯錯，但到目前為止，尚未發現肖傳國在學術上作假。真可惜啊！

看看國內主流媒體. 媒體首頁清一色的站在方舟子一邊, 博客首頁也是一樣, 但當你搜索后就會發現, 普通人的博客並不看好方舟子, 他們對方舟子存在著各式各樣的疑問. 方舟子獨霸江湖的時代已經過去了.

回復  fantasyfun
    肖傳國雖打人犯錯，但到目前為止，尚未發現肖傳國在學術上作假。真可惜啊！
老愚拙 發表於 2010-10-11 02:36

許小可  科學網博客.

http://www.sciencenet.cn/m/user_content.aspx?id=368995

這就是我所知道的肖傳國.

　　脊髓損傷和脊柱裂脊髓脊膜膨出所致大小便失禁無有效治療方法。患者痛苦不堪,常併發泌尿系感染尿毒症最終危及生命。肖傳國教授潛心鑽研18年，融合泌尿外科、神經外科、骨科、顯微外科和神經基礎科學等多學科的知識原始創新，基本解決了這兩大醫學難題。

　　一、在國際上首先提出並證實了「人工體神經-內臟神經反射弧」（簡稱人工反射弧）的神經學新概念。因此獲得國際神經泌尿 Lapides二等獎（1993），美國泌尿學會Fyser 學者獎（2000），吳階平泌尿外科醫學獎（2000），湖北省自然科學獎一等獎（2000）和中國高等學校自然科學獎一等獎（2000）(附件5)，並為國內外權威教科書採納：全國統編教材《外科學》, 第四、五、六版(附件4)；《CAMPBELL』S UROLOGY》（坎貝爾泌尿外科學），P.999-1000, 8th Ed. 2002(附件4)。

　　人工反射弧的基本原理是：將一支體神經運動支近心端與控制膀胱及尿道括約肌的骶神經傳出支遠心端吻合，若體神經運動纖維能再生並替代節前纖維，即形成一人工『皮膚-脊髓中樞-膀胱』反射弧。動物實驗研究顯示：體神經的確能夠再生並替代內臟神經節前纖維而形成人工反射弧，雜交再生的神經纖維具有獨特的形態結構，人工反射弧中有正常的神經遞質產生和轉運；體神經運動神經元所產生的神經衝動可循人工反射弧通路引起膀胱的排尿反射。這項利用異類神經再生以恢復內臟器官功能的原始創新研究先後申請得到美國Paralyzed Veterans of America 基金會、American Paraplegia Society基金會，美國國立衛生研究院(NIH R01DK44877 1993-1997, R01DK53063 1999-2004,皆為PI) (附件4)以及中國國家自然科學基金重點項目、國家傑出青年基金和衛生部臨床重點項目等科研基金資助。

　　二、應用人工反射弧理論和技術，從1995年起治療截癱患者大小便失控獲得成功。因此獲得國家科學技術進步獎二等獎（2001）， 何梁何利基金科學與技術進步獎（2002），國際神經泌尿 Lapides特等獎（2003）(附件5)。

　　該項目的臨床應用研究開始於1995年，現已經治療92例。首期治療的14例截癱病人術后經過了3年隨訪，結果顯示：在所有11例膀胱功能恢復者中，其直腸大便排泄功能亦恢復正常，1例失去隨訪，1例因局部瘢痕過多放棄手術，1例手術失敗。6例高反射性神經原性膀胱患者中，有5例恢復了膀胱儲尿和排尿功能，平均殘餘尿由317毫升下降到29毫升；另外8例無反射性神經原性膀胱患者中，有5例完全恢復膀胱儲尿和排尿功能，平均殘餘尿由288毫升降到32毫升，另有1例部分恢復。

　　1998年，裘法祖院士和國家自然科學基金委員會葉鑫生教授率有關專家赴河南平頂山煤業集團總醫院考查4名截癱礦工建立人工反射弧手術后的療效，對效果非常滿意。1999年衛生部組織成果鑒定，包括7名院士在內的多學科專家一致認為：「人工體神經-內臟神經反射弧理論融合了泌尿外科、神經科、骨科、顯微外科等多學科的知識，成功的建立了體神經-內臟神經反射弧，在臨床上取得了令人鼓舞的療效。這將有可能解決目前我國眾多脊髓損傷病人的大小便失控的問題，極大地提高生活質量和自理能力，而且還能節省大量的醫療費用和人力資源，具有很大的社會效益和經濟效益。人工建立的反射弧這一神經學新概念具有突破性創新意識，其科學研究成果達到國際領先水平」 (附件4)。

　　該成果已經國內外同行重複效果肯定。國外同行亦紛紛邀請講學、手術，尋求合作或對「Xiao』s反射弧」進行研究。肖傳國教授還申請到美國國立衛生院(NIH)252萬美元臨床研究基金（PI: Chuanguo Xiao, R01 DK53063-01A2，10/1999-12/2004），在紐約大學醫學院(NYU)治療截癱病人，亦獲成功。2005年2月德國TUBINGEN大學醫學院邀請肖傳國教授赴德為三位脊髓損傷病人作了人工反射弧手術重建大小便功能。歐洲泌尿雜誌（European Urology,2005 July issue）特邀肖傳國教授撰寫神經性膀胱的Review文章(附件6)。

　　三、擴展人工反射弧理論和技術的應用，治療先天性脊柱裂脊髓脊膜膨出所致大小便失控獲得成功。國際神經泌尿JACKLAPIDES獎評委唯一一次全體同意,再次授於肖傳國2005年的Lapides特等獎,相關論文被評為2004年美國泌尿外科年會Highlight lecture and Take Home Message。Journal of Urology(2005 June issue)並專門為肖教授的文章發Editoral, 稱之為極端重要的文章(an extremely important paper) (附件4)。肖教授2003年被聘為國家973項目首席科學家主持「神經損傷修復和功能重建的應用基礎研究（2003CB515300）」，2004年12月在日本大阪舉行的第4屆亞太神經再生學會上被選為下屆會議主席(2006)。

　　脊柱裂脊髓脊膜膨出是最常見的出生缺陷。每1000例新生兒中發生約1例。主要問題是大小便失禁,這一直是尚未解決的醫學難題之一，無滿意治療措施。自2000年起，在世界上首次應用體神經-內臟神經吻合治療脊柱裂脊膜膨出患兒排尿功能障礙的臨床研究，迄今已成功99例手術。系統長期隨訪2 年以上者共20例，17例手術后8-12月獲得控尿和自主排尿功能。所有獲得排尿功能者大便功能亦隨之正常，與此同時獲得了膀胱/直腸感覺功能（便意）。其餘79例中，已獲初步隨訪41例（術后6－12月）,有效率約為90%; 從方法學上，建立了行之有效的MRI/電生理/術中解剖相結合神經根鑒別法和盡量保留體神經功能的神經根分支吻合術。
　　該成果已經國內同行重複效果肯定。2004年8月衛生部鑒定會包括韓濟生、王正國、鞠  躬、劉允怡、陳宜張、顧玉東、裘法祖等7名院士的多學科專家一致認為：「本項研究很好地解決了長期以來先天性脊柱裂脊膜膨出病人大小便失控的問題，具有巨大的社會效益。借鑒治療脊髓損傷時提出的人工體神經-內臟神經反射弧理論和技術治療脊柱裂脊膜膨出病人大小便失控，具有重要的理論與實際意義和突出的創新性，其科學研究成果達到國際先進水平」 (附件4)。

　　四、學科建設、人才培養和學風道德
　　肖傳國教授將他美國三個實驗室的全套先進設備無償運回國內，籌建成立了神經電生理實驗室、神經形態學實驗室和分子生物學實驗室。主持完成國家自然科學基金重點項目、傑出青年基金項目各一項，衛生部臨床重點項目兩項。1997擔任泌尿外科主任后按國內外高標準進行學科建設和人才培養，建立了結石中心、內窺鏡中心、尿流動力學中心和神經泌尿、小兒女性泌尿、腎移植和泌尿生殖腫瘤專科，還開展了正位可控膀胱再造術、無血前列腺癌根治術、經恥骨複雜性后尿道狹窄成形術、女性壓力性尿失禁微創手術、經陰道轉移肌瓣膀胱陰道瘺修補術等手術，培養中青年骨幹5名,其中4人已晉陞為正教授，博士（生）18名，創建了中南地區第一個泌尿外科研究所。

　　肖傳國教授愛國敬業，淡泊名利，學風端正，治學嚴謹，堅決反對學術浮誇和弄虛作假，以身作則抵制不正之風。

回復  fantasyfun
    肖傳國雖打人犯錯，但到目前為止，尚未發現肖傳國在學術上作假。真可惜啊！
老愚拙 發表於 2010-10-11 02:36

11-30-2006, 07:43 PM    #33  
Wise Young
Administrator


Join Date: Jul 2001
Location: New Brunswick, NJ, USA
Posts: 35,849  Quote:
Originally Posted by BeeBee
The study group will be fowarding their information this week. Possible benefits are: return of bladder function, possible partial return of bowel function (control ability, not sensory) and possible possible sexual return.
Reletively "minor" surgery: a 2 day stay and couple more days at home. (No large incisions or hardware placement: that's OUR definition of major surgery).
Dr Young: do you have links or copies of the published research?


Beebee, I am sorry but I don't have any additional information above what is on Medline and Google, which you have obtained. Dr. Xiao showed videos of his results in the December meeting of the ISCITT meeting in December (Source). I have to say that the videos of the urinary streams of his patients when they scratched their buttocks was quite amazing. Chuan-Guo Xiao, M.D. received the Grand Prize, International Jack Lapides Award on Urodynamic and Neurourology Research. If you do a search on internet, you will find a variety of articles about a controversial lawsuit that Dr. Xiao seemed to have been involved in. I have met the man several times and think that he is a legitimate urologist and very much committed to this procedure for improving the lives of people with spinal cord injury.

Wise.

The clinical trial information is on
http://www.med.nyu.edu/fgpurology/clinical/

Quote:
Spinal Cord Injury

Title: Skin-CNS-Bladder Reflex Arc for Micturition after SCI

Prinicipal Investigator: Chuan-Guo Xiao, M.D.

Purpose: The purpose of this research is to restore bladder function after a spinal cord injury and allow the subject to have voluntary control of bladder emptying. Since the spinal cord injury, the subject must have difficulty urinating and need assistance with a tube to insert into their bladder to allow urine to flow. As a part of this study, the subject would undergo a surgical procedure in which two of their nerves which have been paralyzed below the level of their spinal cord injury will be connected to other nerves, hoping to regenerate the paralyzed ones. Normally, it takes 12-18 months for these nerves to regenerate so that the subject will not have any change in their current bladder function until 12-18 months after their surgery. At that time, the subject would voluntarily start their urination by scratching their skin.  

The description of the procedure is given at


Quote:
4) Dr. Chuan-Guo Xiao and colleagues (Wuhan, China & New York, USA) have rerouted nerves below the injury site, restoring the patient』s ability to control urination through skin stimulation (J Urol, 170, 2003; & European Urology 49, 2006). As illustrated, the lumbar-level L5 ventral nerve root is usually connected to the sacral-level S3 (or S2) ventral nerve root. (The ventral and dorsal roots contain nerves that leave and enter the spinal cord, respectively). After rerouting, by scratching, gently squeezing, or electro-stimulation of the skin associated with the L5 dermatome, a voiding response is initiated. Basically, these actions trigger a sensory signal that enters the cord via the L5-dorsal root, in turn, stimulating nerves that leave the cord through the L5-ventral roots now connected to the bladder-controlling S3-ventral nerve root. Provided this area of rerouting is undamaged, the procedure is suitable for all levels of injury. Because this procedure does not restore bladder sensation, patients need to consciously initiate the triggering procedures for urination.



In his 2003 article, Xiao reported the results of treating 15 patients with complete, ASIA-A injuries with this procedure. Injuries ranged from C4 to T12; in other words, all were well above the nerve-rerouting area. The time between injury and surgery averaged 6.8 years, and average follow-up was three years. Of the 15 patients, 10 recovered bladder-storage and emptying function starting about a year after surgery (the time for regenerating neurons to reach their target site), residual urine decreased from 332 to 31 milliliters, and urinary-tract infections became negligible. In addition, two patients partially recovered, requiring electrical stimulation to initiate voiding, and, although decreasing residual urine, still retaining over 100 milliliters. Of the three remaining patients, one was lost to follow-up, and two did not accrue benefits, apparently due to poor rerouting connections.

Before surgery, six of the 12 patients who eventually recovered bladder control had elevated serum creatine levels, an indicator of kidney problems. A year and half after the procedure, their creatine levels returned to normal. In addition, patients who regained bladder control also regained bowel control. Overall, by the end of 2004, 81 of 92 treated patients regained bladder function one year after surgery.

回復  fantasyfun
    肖傳國雖打人犯錯，但到目前為止，尚未發現肖傳國在學術上作假。真可惜啊！
老愚拙 發表於 2010-10-11 02:36

Experimental surgery helps relieve kids with spina bifida and spinal injuries
By John Barry, Times Staff Writer
In Print: Sunday, March 15, 2009

Adam Byrum, 10, messes up his mother』s hair a few minutes before being taken to surgery at All Children』s Hospital on Thursday. Adam has had 19 surgeries since a tumor appeared on his spine, but his mother says he hasn』t complained about them.  
  
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Chuan-Guo Xiao, a urologist from China, invented the procedure that reroutes nerves in the spine to provide a new pathway for voluntary stimulation of the bladder. Here, he instructs surgeons at All Children』s Hospital performing it.

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ST. PETERSBURG

Adam Byrum is a 10-year-old kid nicknamed "Wheels." He jumps curbs, flies off ramps, drives a motorized dirt bike, and is the limbo champion at school. He also frankly calls himself an "experiment."

Thursday and Friday, Adam and a group of other children were literally rewired by surgeons at All Children's Hospital. Nerves in their spinal cords were rerouted and reconnected in an attempt to rescue them from the invisible hells of bladder and bowel paralysis. The rewiring surgery is imported from China. It's experimental, it's expensive, it's uninsured.

It has been attempted on only a handful of American children with mixed results.

Now it's the heart of a three-year study at All Children's that may eventually involve 100 children who suffer from spinal cord injuries or the birth defect spina bifida. Surgeons launched the project with eight operations, including Adam's.

Pediatric urologist Yves Homsy and neurosurgeons Gerald Tuite and Luis Rodriguez traveled to China last November to learn the rewiring procedure. They brought its inventor here to offer advice during the first eight surgeries. "I'm sure there are skeptics among us," Homsy told a gathering of doctors on Thursday night. "I'm not the least among them." But he said it offers a hope that both doctors and parents are desperate for.

Adam Byrum is also not the least among the skeptics. This rewiring was his 19th surgery since a tumor appeared on his spinal cord when he was 9 months old. He lost a kidney last year and needs dialysis three times a week, each dialysis requiring a two-hour round-trip from his home in Thonotosassa. He is on a kidney transplant list.

He is a clear-eyed, hardened medical veteran, who doesn't smile when he uses the word "experiment."

But he is also as daring as they come. Adam won that school limbo championship in a wheelchair.

• • •

The rewiring is called the "Xiao procedure." It was invented by Chuan-Guo Xiao, a urologist who has performed the surgery on about 1,500 children and adults in China who are paralyzed by spinal cord injuries or suffer from spina bifida.

The Xiao procedure is meant to bring relief to people with paralyzed bladders and bowels. It doesn't just get a patient out of diapers. It alleviates the ravages of urinary infections and kidney failure. Many parents of children with spina bifida fear their kids are doomed to dialysis before they turn 20.

The surgery sounds outrageous. It involves rewiring the spinal cord so that sacral nerve roots leading to the bladder and bowels are spliced to a lumbar nerve root leading to the thigh.

If it works, the results are weird, but phenomenal. The bladder and bowels are activated when the patient vigorously scratches a spot on his or her thigh.

Xiao claims an 87 percent success rate.

The Xiao procedure was made a pilot study two years ago at the William Beaumont Hospital in Royal Oak, Mich. Surgeons performed the Xiao on nine kids with spina bifida and three with spinal cord injuries. Funds were raised to cover the cost of each surgery — between $40,000 and $50,000. The team was led by the hospital's urology chairman, Kenneth Peters, who had traveled to China.

Peters, Xiao and the All Children's surgeons will speak at the First World Conference on Spina Bifida Research this week in Orlando.

By telephone last week, Peters called the results of the pilot at Beaumont "mixed."

Twelve children got the surgery — three with spinal cord injuries, nine with spina bifida. The three with spinal cord injuries were not helped by the procedure. Seven of the nine with spina bifida saw "marked improvement." One of them was a "home run," a girl who achieved complete continence.

Peters said the major complication was leg weakness that developed among eight of the nine with spina bifida. All had been able to walk before the surgery. They often required intense physical therapy, Peters said, "just to get them back to baseline." One child developed drop foot, meaning he could not raise his foot when he walked.

"We knew there could be complications going in," he said, "but it was still frustrating."

When Peters addresses the conference this week, he will emphasize caution. Parents are desperate for help, he said. But because of the unknowns, "if a parent walked into my office and stuck $50,000 in my face, I'd have to say no."

The surgeries should continue, he said, only under the strictest research protocol until U.S. doctors see the kind of results that Xiao reports in China. Beaumont will perform four more Xiao procedures in May.

Peters: "Do the benefits outweigh the risks? I'm not ready to say that. It's very easy to be wowed by it. I was wowed in China when I saw Dr. Xiao's data. I'm still wowed, but my 'wow' is a little more tempered."

• • •

The cautious findings in Beaumont and virtual absence of other U.S. data prompted intense debate at All Children's. Urologist Homsy said the three-year study had to go before the hospital's Institutional Review Board and was okayed only after lengthy review and a set of strict research conditions.

Most of the children being chosen are already in wheelchairs, so complications of leg weakness and drop foot will be less of a concern.

All of the spina bifida children require spinal cord surgery anyway. Spina bifida is a birth defect that occurs early in pregnancy. Two sides of the embryo's spine fail to grow together, leaving an opening. The spinal cord pushes through the opening, destroying many nerve ends. Soon after birth, surgeons close the opening. But that leaves scar tissue that can cause later neurological problems. Kids have to be operated on as they grow to trim away the scar tissue. The procedure is called "detethering."

Except for Adam Byrum, who doesn't have spina bifida, the other seven children operated on this week needed detethering.

Their parents were told that the All Children's study is a blinded one. That means there is a control group that gets the detethering, but does not get the Xiao procedure. The parents won't know who got what until the study is over. Even Homsy doesn't know which of the spina bifida children are in the control group or the Xiao group.

The only kid who knows he got the Xiao is Adam.

One of the children who doesn't know is 4-year-old Sojourna Covelli of Valrico. She was born with a hole in her back to a 13-year-old mother. She was taken in as a foster child by Linda and Richard Covelli, who care for three other foster children with medical needs.

The Covellis call Sojourna "Journey." They adopted her about a year ago. She has had 18 surgeries. She was operated on Friday morning.

The Covellis know the odds are only 50-50 that she got the Xiao.

"I'll take those odds any day," Linda Covelli said.

The Covellis believe she will get the surgery eventually, even if she is in the control group. But they say they have prayed so hard they are sure that God got her in the Xiao group.

They even bought Journey her first pair of Hannah Montana underpants.

"What are we here for?" Linda Covelli asked her as they waited for surgery on Friday.

Journey shouted:

"The Xiao!"

• • •

Thursday, Adam Byrum lay cloaked in blue fabric as lead neurosurgeon Sarah Gaskill operated. Other lead surgeons last week were Tuite and Dr. Carolyn Carey. All that could be seen of Adam were his small bare feet and his open spinal cord. Xiao watched on a giant TV monitor. Adam was there for three hours.

After his Xiao, Adam spent Thursday and Friday in intensive care and on dialysis. He slept most of the time.

He was doing fine.

He has never complained about his many surgeries, his mother, Toni, said, though "he has said he's sick and tired of it." When he arrived at All Children's last week, he was wearing a "Just Do It" T-shirt.

Now, the neurological healing and nerve regeneration will take at least eight months.

Then Adam will find out if he can change his life just by scratching his thigh.

John Barry can be reached at jbarry@sptimes.com or (727) 892-2258.


[Last modified: Mar 17, 2009 10:28 AM]

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